Eight-year-old Jack, his seven-year-old sister, Annie, and Peanut the mouse ride in a tree house to the Amazon rain forests, where they encounter giant ants, flesh-eating piranhas, hungry crocodiles, and wild jaguars.

Wilbur, the pig, is desolate when he discovers that he is destined to be the farmer's Christmas dinner until his spider friend, Charlotte, decides to help him.